The FDA has given a green light to a hydrogel applicator that can be quickly deployed to help stem severe, life-threatening bleeding within seconds.

Pfizer and BioNTech may have a strong pedigree in the mRNA vaccine game, but, when it comes to flu, they’ve run up against the same problem as their peers—neutralizing influenza strain B.

Céline Dion stands alone as a singer, a chart-topping ballad-belter who recorded some of the most iconic songs of all time, including “My Heart Will Go On” from the “Titanic” soundtrack. But, in 2022, Dion made headlines not for her one-in-a-million voice, but for a one-in-a-million diagnosis: a rare neurological disease called stiff-person syndrome (SPS).

Researchers at UC Davis have used a brain-computer interface implant to help restore a patient’s voice, after ALS had slowly robbed him of his ability to speak clearly.

At Bayer, a groupwide restructuring is being rolled out as a top priority. But, to Juergen Eckhardt, M.D., who leads both the investment arm Leaps by Bayer and the pharma business development team, the ongoing overhaul won’t disrupt the German company’s dealmaking appetite.

Turnstone Biologics is narrowing the focus of phase 1 trials of its lead tumor-infiltrating lymphocyte (TIL) therapy, with cutaneous melanoma and breast cancer no longer in the mix.

After Arrowhead Pharmaceuticals cleared out its work on a clinical-stage cardiovascular candidate, the company is filling the blank space with two obesity assets, both set to enter the clinic in early 2025.

Antisense oligonucleotides (ASOs), which bind to RNA and prevent them from being translated into proteins, have gained popularity in recent years as a way to treat neurodegenerative diseases. However, getting these drugs into the brain has been challenging, currently requiring invasive infusion directly into the cerebrospinal fluid.

Designing a clinical trial is hard work. Silicon Valley tech company Medable is hoping to make it easier with their newly launched Medable Studio, an all-in-one platform for configuring, translating, validating and launching Medable’s software solution into clinical trials.

In 1933, geneticist Thomas Hunt Morgan won the Nobel Prize in Physiology or Medicine for demonstrating that genes exist on chromosomes, which are passed down from parent to offspring. Ninety-one years later, researchers at Columbia University—the same school where Morgan conducted his award-winning fruit fly research—have found a gene that violates this cardinal rule.