Frequency Therapeutics regroups as hearing loss med falls short in phase 2

Frequency Therapeutics is going back to the drawing board. After showing promise in phase 1, four dosing regimens of its hearing loss treatment did no better than placebo in a phase 2a study. The company will press ahead with a single-dose regimen and is waiting on final results from this study as well as readouts from two more phase 1b studies to plot its next steps.

Odonate abandons breast cancer chemo drug, closes its doors

Odonate Therapeutics is ending development of its oral chemotherapy drug and closing up shop after the FDA deemed the drug’s clinical data “unlikely to support FDA approval.” As it winds down its operations, the company will work with clinical sites to switch patients participating in its clinical trials to alternative treatments, the company said in a statement Monday.

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