Amicus Therapeutics Inc. (FOLD) had a rough trading day for Friday October 04 as shares tumbled 9.98%, or a loss of $-0.87 per share, to close at $7.85. After opening the day at $8.69, shares of Amicus Therapeutics Inc. traded as high as $8.73 and as low as $7.79. Volume was 5.38 million shares over 25,713 trades, against an average daily volume of n/a shares and a total float of 254.63 million.

Heron Therapeutics Inc. (HRTX) had a rough trading day for Friday October 04 as shares tumbled 10.04%, or a loss of $-1.945 per share, to close at $17.42. After opening the day at $18.17, shares of Heron Therapeutics Inc. traded as high as $18.49 and as low as $17.25. Volume was 6.84 million shares over 40,087 trades, against an average daily volume of n/a shares and a total float of 79.82 million.

Exelixis Inc. (EXEL) had a rough trading day for Friday October 04 as shares tumbled 5.02%, or a loss of $-0.9 per share, to close at $17.04. After opening the day at $17.96, shares of Exelixis Inc. traded as high as $17.98 and as low as $16.94. Volume was 3.65 million shares over 26,237 trades, against an average daily volume of n/a shares and a total float of 302.91 million.

Among the S&P 500’s biggest fallers on Friday October 04 was Murphy Oil Corporation (MUR). The stock experienced a 4.34% decline to $20.95 with 3.9 million shares changing hands.

Atlas Financial Holdings Inc. (AFH) had a good day on the market for Friday October 04 as shares jumped 13.54% to close at $0.37. About 116,337 shares traded hands on 311 trades for the day, compared with an average daily volume of n/a shares out of a total float of 11.94 million. After opening the trading day at $0.35, shares of Atlas Financial Holdings Inc. stayed within a range of $0.38 to $0.35.

October 04 was a positive day for Trican Well Service Ltd. (TCW:CA) as its stock finished the day having gained 8.33% to hit a price of $1.04 a share. The company reached a market cap of 300.83 million and has 288.48 million shares outstanding. Trican Well Service Ltd. is a component of the the S&P/TSX SmallCap Index.

Among the biggest risers on the S&P 500 on Friday October 04 was Allstate Corporation (The) ($ALL), popping some 2.66% to a price of $108.46 a share with some 1.71 million shares trading hands.

Destination XL Group Inc. (DXLG) had a rough trading day for Friday October 04 as shares tumbled 6.37%, or a loss of $-0.1 per share, to close at $1.47. After opening the day at $1.57, shares of Destination XL Group Inc. traded as high as $1.57 and as low as $1.45. Volume was 53,408 shares over 358 trades, against an average daily volume of n/a shares and a total float of 49.96 million.

Pfenex Inc. (PFNX) had a rough trading day for Friday October 04 as shares tumbled 6.05%, or a loss of $-0.48 per share, to close at $7.46. After opening the day at $7.97, shares of Pfenex Inc. traded as high as $8.00 and as low as $6.96. Volume was 634,974 shares over 3,131 trades, against an average daily volume of n/a shares and a total float of 31.6 million.

VirnetX Holding Corp (VHC) had a rough trading day for Friday October 04 as shares tumbled 6.23%, or a loss of $-0.39 per share, to close at $5.87. After opening the day at $6.26, shares of VirnetX Holding Corp traded as high as $6.53 and as low as $5.71. Volume was 1.06 million shares over 5,099 trades, against an average daily volume of n/a shares and a total float of 68.95 million.